Nancy Guthrie Investigates: Top FBI Official Provides Important Update on Newly Discovered ‘Critical DNA’ Claim

On April 16, 2026, ABC News Channel X announced that federal investigators “received and are analyzing potentially critical DNA recovered from a home in Tucson, Arizona.” Nancy Guthrie”, citing a source familiar with the investigation.

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Earlier, DNA samples failed to produce a match in the mix DNA Index System (CODIS), which is the FBI’s database of criminal offenders or individuals who are determined to be “mixed” with another person’s DNA.

84-year-old mother Nancy Savannah GuthrieOn February 1, 2026, the anchor of NBC’s “Today” show disappeared after being visited by his family after missing a church service. Authorities said she was likely abducted in the early morning hours because her pacemaker lost connection with her phone around 2:30 a.m., indicating the device was out of range.

More than two and a half months have passed since the investigation into Nancy Guthrie’s disappearance began, but so far no suspects have been identified and the search continues.

“This is a situation where we need this information to be able to exclude people or exclude people. So in a situation like this where we don’t actually have a lot of digital forensic evidence, which is obviously what the FBI is very good at, really, it becomes very, very important,” Wald told NewsNation.

“As we’ve seen, we have a distinct lack of video forensic evidence, as well as actual phone calls and that type of forensic evidence, so I think there’s no question in this case that the hair was important in determining who was in and out, and the FBI may have to investigate whether they can figure out who it was,” she added.