In a major healthcare shift, the UAE approved Foundayo (orforglipron), a once-daily oral weight loss drug developed by Eli Lilly. The UAE Medicines Authority’s decision makes the country one of the first countries in the world to launch a needle-free alternative to injectable weight loss treatments.The approval comes as obesity is increasingly linked to serious long-term conditions, including type 2 diabetes, cardiovascular disease and certain cancers. Foundayo’s convenience makes it stand out. Unlike injectable GLP-1 drugs, it is taken as a simple daily pill and does not require strict meal or drinking times, making it easier for patients to adhere to treatment.
Despite Foundayo’s growing popularity, it’s not suitable for casual or cosmetic use. It is only available by prescription and under strict medical supervision. Doctors across the UAE should follow clear eligibility guidelines before recommending the drug.Patients generally qualify if they have a body mass index (BMI) of 30 or above, which is clinically obese, or a BMI above 27 with related health conditions. These include metabolic and lifestyle diseases such as diabetes, high blood pressure, high cholesterol, sleep apnea and joint stress conditions.Before starting treatment, patients will receive a detailed medical evaluation. These include blood tests, metabolic screening and a thorough medical history review. Specialists such as endocrinologists and internal medicine specialists will play a central role in determining whether a drug is appropriate, ensuring that its use is targeted and medically justified.
Fodayo belongs to a class of drugs called GLP-1 receptor agonists, which mimic natural hormones in the body that regulate appetite and blood sugar levels. In effect, the drug works by helping patients feel full earlier, reducing hunger signals, and lowering overall calorie intake without imposing strict dietary restrictions.Clinical trials show strong and consistent results. Patients taking higher doses experienced an average weight loss of up to 12.4%, with some studies reporting weight losses of around 12kg over 72 weeks. In addition to weight loss, early findings show improvements in cholesterol levels, blood pressure and markers associated with heart disease risk, suggesting broader metabolic benefits.At the same time, doctors warn that side effects are possible, especially in the early stages of treatment. Some patients report nausea, mild digestive discomfort, and gastrointestinal problems, especially as dose levels are increased. These effects are usually manageable but highlight the importance of medical supervision throughout treatment.
The drug is expected to be available in pharmacies in the UAE from May 2026, but access will still be controlled through prescription channels. Health experts make it clear that Foundayo is not a shortcut or a one-time solution. Instead, it is designed to be part of a long-term treatment plan.In many cases, patients may need to take medication long-term, sometimes for life, depending on their condition. Doctors stress that stopping medication without making lifestyle changes, such as eating a balanced diet and exercising regularly, may lead to weight regain. This medication works best when combined with ongoing behavioral changes rather than replacing them.There are also clear medical exclusions. This medication is not recommended for use by pregnant or breastfeeding women and may not be suitable for individuals with certain thyroid cancers, endocrine disorders, or severe gastrointestinal and kidney disease. These limitations emphasize the need for careful screening before initiating treatment.
While the official price of Foundayo in the UAE has not yet been determined, early estimates suggest it may be positioned in the same range as existing GLP-1 treatments. Injectable alternatives currently available in the UAE typically cost between Dh800 and Dh1,500 per month, depending on dosage and brand.Industry experts expect Foundayo’s pricing to be competitive in this range, although word of mouth could impact final pricing based on demand and insurance coverage. Another key factor is whether UAE insurance companies classify the drug as a primary obesity treatment or an elective treatment, which could significantly impact patients’ out-of-pocket costs.Affordability may play a crucial role in the adoption process. While the convenience of taking the drug daily is expected to attract strong demand, long-term use means pricing and insurance support will ultimately determine treatment accessibility.
UAE regulators have made it clear that Foundayo’s approval is a controlled medical procedure and not a mass-market weight loss solution. The drug was approved only after a detailed scientific review of its safety, effectiveness and performance in clinical trials, the UAE Medicines Authority said, positioning it as part of the country’s wider strategy to tackle rising obesity rates.In its official statement, the agency stressed that the move reflects the UAE’s commitment to providing advanced treatments to patients while maintaining high regulatory standards. Dr. Fatima Al Kaabi, Director-General of the agency, noted that addressing obesity remains a national priority as it is linked to more than 200 diseases, including diabetes, hypertension and cancer. She added that the approval signals a shift toward more patient-friendly treatments.Medical experts also point to safety considerations related to the GLP-1 receptor agonist class of drugs. Clinical data show that this treatment may cause mild to moderate gastrointestinal side effects such as nausea and vomiting, especially in the early stages or at higher doses.The regulator further emphasized that the drug is not a stand-alone treatment. It is designed for long-term use as part of a structured obesity management program that includes lifestyle changes such as diet and physical activity. By combining strict prescribing controls with ongoing monitoring, UAE authorities aim to ensure treatment innovation does not come at the expense of patient safety, while expanding access to effective weight management solutions.[Note: The information provided in this article is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any new medication or treatment and before changing your diet or supplement regimen.]
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